Molecular Phylogenetics


Aims of
the course:
To introduce the theory and practice of phylogenetic inference from molecular data.

To introduce some of the most useful methods and computer programmes.

Preliminary
timetable:
Part 1: Basic sequence handling and analysis methods (days 1-2).
Part 2: Phylogenetic inference from molecular sequence data (days 3-5).
_____
  • Day 1:
    • Lectures
      • Introduction to the course.
      • Bioinformatics services at ABC (Hungarian EMBnet Node)
      • An introduction to UNIX and Linux
    • Practical
      • Working with UNIX and Linux
  • Day 2:
    • Lectures
      • Sequence databanks, sequence formats
      • The EMBOSS software package
    • Practical
      • Basic sequence handling and analysis using EMBOSS programs
  • Day 3:
    • Lectures
      • Multiple sequence alignment.
      • Characters and data.
    • Practical
      • Multiple sequence alignment.
  • Day 4:
    • Lectures
      • Distance matrix methods.
      • Maximum Likelihood and Bayesian methods.
    • Practical
      • Nucleotide-based phylogenies.
  • Day 5:
    • Lectures
      • Robustness of data and hypotheses.
      • Summary.
      • Round table discussion.
    • Practical
      • Protein-based phylogenies.
Lecturers,
instructors:
James McInerney and David Fitzpatrick (part 2),

Endre Barta and Gábor Tóth (part 1)

Course
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